A single test for suspected chronic Lyme borelliosis is often not enough. If you suspect to have chronic Lyme borelliosis, the following tests are recommended:
1. Borrelia Elispot
The Borrelia EliSpot reflects the actual Borrelia burgdorferi activity of chronic and recent Borrelia burgdorferi infections. It is highly sensitive and can detect even one single Borrelia burgdorferi-reactive T-cell in the sample. With detection levels that can be as low as one cell in 100,000, this test is one of the most sensitive cellular assays available. The EliSpot is between 20 and 200 times more sensitive than a conventional ELISA.
Results should usually be negative about 4 to 8 weeks after completion of an effective therapy.
Clinical research studies and case studies have shown that chronic Lyme infections are often accompanied by changes in the cellular
immune defence. The CD57+ cells document the extent of the immune suppression of chronic Lyme disease.
3. Borrelia IgG/IgM Seraspot
The SeraSpot MicroArray analyses the Borrelia burgdorferi IgG- and IgM-antibodies and Borrelia burgdorferi subspecies.
We offer all together as a bundle from ArminLabs in Germany. The price includes all three tests, the blood sampling, courrier charges, a written report and if necessary a prescription.
Borrelia burgdorferi is able to survive in infected tissues for years or decades. A study from 2006 found Borrelia burgdorferi cells in the brain of patients who suffered from chronic Lyme neuroborreliosis. The persistence of these bacteria, and the fact that they were found inside nerve cells may explain the long latent stage and persistence of Borrelia infection. The detection and recognition of bacteria is essential for the diagnosis and the treatment.
Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis. J Neuroinflammation. 2008; 5: 40.
Judith Miklossy,1 Sandor Kasas,2 Anne D Zurn,3 Sherman McCall,4 Sheng Yu,1 and Patrick L McGeer1
Turnaround time: approx. 1-2 weeks