Studies suggested an association between low serum magnesium levels and metabolic or cardiovascular disease and several studies have shown that low serum magnesium is associated with vascular calcification.
A study analysed 34,553 participants as part of a health examination program in a Korean population at low risk for cardiovascular disease. Low serum magnesium was associated with coronary artery calcification (CAC) after adjustment for age, sex, BMI, diabetes, hypertension, cardiovascular disease, systolic BP, LDL cholesterol, HDL cholesterol, eGFR, serum calcium and phosphorus, high-sensitive CRP, current smoking status, alcohol intake and vigorous exercise frequency.
A lack of magnesium is also linked to constipation and muscle cramps.
We recommend to take 400 mg Magnesium daily, ideally as a Magnesium Citrate as this is well absorbed. The upper safety limit for an adult is 1600 mg daily. Too much magnesium can lead to loose stools.