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Lifecodex MTHFR Genetic Testing



Methylation is critical for keeping your body and brain biochemistry in balance.

Common genetic variants (SNPs) can impact our natural ability to methylate and thus result in increased susceptibility to systemic imbalances and chronic health conditions including heart disease, depression, diabetes, chronic fatigue, autoimmune disease, poor foetal development and premature ageing.

An elevated homocysteine level is known to be an independent risk factor for ischaemic stroke, thrombotic and cardiovascular diseases. Homocysteine is an amino acid synthesised by the body. In the presence of adequate levels of Folate, vitamin B6 and vitamin B12, homocysteine is either metabolised to cysteine or methionine in a process called methylation. A deficiency in any one of these b-vitamins can cause homocysteine levels to rise.

Research has shown that many individuals may be at risk of methylation insufficiency due to reduced MTHFR enzyme function.

Additional Information

The MTHFR SNPs only provide part of the picture, and often issues with other parts of the cycle – e.g. B12/ re-methylation can be as impactful as those involving folate.

The Lifecodex MTHFR Panel tests additional genetic factors to have a deeper insight into methylation related issues.


  • personalised, colour coded genotype results
  • gene function and SNP impact descriptions
  • clinically relevant SNPs
  • nutrient and other epigenetic impacts
  • follow up functional testing options
  • nutrition and lifestyle recommendations
  • dynamic links to research evidence

Genes included:

Methionine Cycle: AHCY, BHMT, FUT2, MAT1A, MTR, MTRR, PEMT and TCN2
Neurotransmitter Cycle: COMT, MAOA, MAOB, PNMT, QDPR andVDR
Transsulphuration Cycle: CBS, CTH, GSS, MUT and SUOX
Urea Cycle: NOS and SOD

If you like to discuss the results, please get in touch with one of our affiliate practitioners.

Click here to download a sample report